DM660 Single Channel Dummy Membrane

 

The DM660 is an electronic dummy membrane used to simulate an Ussing experiment. It is useful both in verifying the function of the voltage/current clamp and as a learning aid. This device is compatible with the VCC600.

The DM_MC6 is an input device for connecting voltage and current electrodes to the VCC MC2, VCC MC6, and VCC MC8 instruments. The DM MC6 is a small, shielded unit that can be mounted close to individual Ussing chambers and is recommended for use with both our EasyMount Ussing Chamber Systems or for classical Ussing chamber systems. Each DM MC6 also contains a single channel “dummy membrane” for use in testing the the functionality of voltage/current clamp.

Input jacks: 2 mm pin tip. Connection to voltage/current clamp: choice of 4’ or 7’ shielded cable with modular plugs. One DM MC6 is required for each clamp channel.

The DM6 contains six individual electronic equivalents of an epithelial tissue (i.e., - dummy membrane) that connect to the VCC MC6 via a flat ribbon cable. This device is a convenient tool for learning the features of the VCC MC6 without setting up an experiment and it provides a mechanism for verifying the operating condition of the instrument when problems are encountered during an experiment.

This six channel black anodized aluminum electrode input panel is designed to interface directly with the 6-channel vertical diffusion chamber system now owned by Harvard Apparatus as purchased from Navicyte, Inc. (formerly Precision Instruments Design) or Corning/CoStar. The EP MC6 mounts directly behind the heat block and in front of the air valve manifold. Short electrode leads (P/N P2024, not included) connect current and voltage electrodes to the pintip input jacks. Connection to the VCC MC6 is by way of a flat cable assembly (included).

The VCC MC2 is a modular two-channel voltage/current clamp with clamp channels that are interchangeable with those of the VCC MC6 and VCC MC8. It includes an integral pulse generator and computer interface circuitry in a small 9.5” chassis while maintaining nearly all the features of the single channel VCC600. The instrument reduces the amount of lab bench space required for transepithelial experiments and interfaces perfectly with our EasyMount two channel tissue and cell culture chambers systems. Each VCC MC2 includes two (2) single channel input boxes (DM MC6).

Option: ±35 V output compliance

The VCC MC6 is a modular, multichannel voltage/current clamp that combines up to six individual voltage/current clamp units, a pulse generator and computer interface circuitry in a single 18" chassis while retaining nearly all the functionality of the single channel VCC600. The instrument markedly reduces the amount of lab bench space required, interfaces with the EasyMount chamber systems listed below, and makes controlling multiple tissues much more convenient. The VCC MC6 features a Master Override control which when activated permits simultaneous control of all voltage/current clamp channels using a single set of switches. Option HV increases the output compliance to ± 35V DC. This is required only for certain types of experiments. Please consult the manufacturer.

Each VCC MC6 may be purchased with either the individual DM MC6 modules with integral test dummy membrane or the EP MC6 six channel electrode input panel.

The VCC MC8 is an “extended” chassis version of the VCC MC6 multichannel voltage/current clamp so that it accommodates a total of 8 voltage/current clamp modules in a 24” wide chassis. Otherwise, the instrument has the same features as the VCC MC6 including the extremely useful Master Control feature and single cable interface to our ACQUIRE & ANALYZE data acquisition system. This unit is available only with the DM_MC6 input modules above. Option HV increases the output compliance to ± 35V DC. This is required only for certain types of experiments. Please consult the manufacturer.