The new chamber system design that includes individual Ussing chambers, a heating block for temperature control, needle valves for adjustment of gas flow used for oxygenation and gas lift stirring, Ag/AgCl reference electrodes for measuring transepithelial voltage and passing current and leads for connecting the electrodes to the voltage/current clamp. The system has been designed for both ease of use and easy cleanup. Tissues and cell culture inserts are first placed into a special holder that is then simply slid into position in the chamber. Unlike other systems, the chambers do not have to be removed from the heat block nor do the electrodes have to be disturbed, etc. Pricing for the systems depends on the number and type of chambers selected as given below. Please consult factory for a complete description and to discuss the chamber design most suited for use with your tissue samples and experiments.